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TOXICITY IN ANIMALS
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"The genus Fusarium contains important mycotoxin-producing
species that have been implicated in ... several animal diseases,
including hemorrhagic, estrogenic, emetic, and feed refusal syndromes,
fescue foot, degnala disease, moldy sweet potato toxicosis, bean hulls
poisoning, and equine leukoencephalomalacia. The interest in toxigenic
Fusarium species is increasing world_wide due to the discovery of a
growing number of naturally occurring Fusarium mycotoxins that have
practical importance as threats to human and animal health."
quoted from Toxigenic Fusarium
Species by Marasas et alia, Penn State U, 1984
EFFECT ON MAMMALS: First Report of Production of Fumonisins B1, B2,
and B3 from Fusarium oxysporum var redoleaans [http://www.nal.usda.gov/ttic/cgi_bin/tektran_abs_printV3.pl/ttic/tektran/data/
oooo5/98/0000059895.html?mycoherbicide#first_hit}
This ARS (Agricultural Research Service) report (#0000059895)
Interpretive summary points out that :
"FB1 is an important phytotoxin and mammalian toxin. This is the
first report of fumonisins produced by Fusarium oxysporum which is a
well-known pathogen of economically important crops. It is possible that
the fumonisins are involved in the pathogenesis of F.oxysporum."
(Bold within entries is our emphasis throughout.)
Significance: Since in the keywords "mycoherbicide" is
listed, one assumes that the study looks at Foxy as a mycoherbicide and
therefore has serious implications for the use of Foxy as a
mycoherbicide. This shows that Foxy does, indeed, produce recognized
toxins.
EFFECT ON MAMMALS: N-Acetyl Derivatives of Type C Fumonisins produced
by Fusarium oxysporum. N-acetyl derivatives are usually more
soluble in bodily fluids than their unacetylated congeners.
[http://plaza.snu.ac.kr/~agbiotek/english/researchtopics06.html]
This is a research project done at the School of Agricultural
Biotechnology, Seoul National University
• Seo JA, Kim JC, Lee YW (1999) Journal of Natural Products 62(2):
355-357 (SCI, 1.432)
• Seo JA, Kim JC, Lee YW (1996) Isolation and Characterization of
Two New Type C Fumonisins Produced by Fusarium oxysporum. Journal of
Natura Products 59 : 1003-1005 (SCI, 1.432)
Significance: Fumonisins as indicated above are mammalian toxins.
This reinforces finding by ARS that Foxy can produce this toxin which
can affect mammals, which by definition include humans.
Also see: FUSARIUM, TRIGO Y CEBADA, RIESGOS - (URUGUAY) (02)
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